1,4,9-三甲基-9H-咔唑合成路线 （共 8 条）
反应条件
1: 1,4-dimethyl-9H-carbazole With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 0.25 h; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide; mineral oil T=0 - 20°C; Inert atmosphere;
参考文献
Deane, Fiona M.; O'Sullivan, Elaine C.; Maguire, Anita R.; Gilbert, Jayne; Sakoff, Jennette A.; McCluskey, Adam; McCarthy, Florence O.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 8 p. 1334 - 1344
反应条件
montmorillonite K-10 T=90°C; 0.166667 h; microwave heating;
参考文献
Abid, Mohammed; Spaeth, Andrew; Toeroek, Bela
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 15 p. 2191 - 2196
反应条件
montmorillonite K-10 T=170°C; Friedel Crafts alkylation; 0.5 h; Microwave irradiationneat (no solvent);
参考文献
Kulkarni, Aditya; Quang, Phong; Toeroek, Bela
Synthesis, 2009 , # 23 art. no. M02409SS, p. 4010 - 4014
反应条件
1: toluene-4-sulfonic acid / ethanol / 2 h / |Reflux 2: sodium hydride / N,N-dimethyl-formamide / 20 °C View Scheme
参考文献
Deane, Fiona M.; O'Sullivan, Elaine C.; Maguire, Anita R.; Gilbert, Jayne; Sakoff, Jennette A.; McCluskey, Adam; McCarthy, Florence O.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 8 p. 1334 - 1344
反应条件
1.1: sulfuric acid; silica gel / dichloromethane / 120 h 2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C / Inert atmosphere 2.2: 0 - 20 °C / Inert atmosphere View Scheme
参考文献
Deane, Fiona M.; Miller, Charlotte M.; Maguire, Anita R.; McCarthy, Florence O.
Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 4 p. 814 - 823
反应条件
ammonia; sodium amide und Behandeln der Reaktionsloesung mit Methyljodid;
参考文献
Robinson; Saxton
Journal of the Chemical Society, 1953 , p. 2596,2599
参考文献
Robinson; Saxton
Journal of the Chemical Society, 1953 , p. 2596,2599
Full Text Show Details
Cranwell; Saxton
Tetrahedron, 1964 , vol. 20, p. 877
参考文献
Robinson; Saxton
Journal of the Chemical Society, 1953 , p. 2596,2599
