3-甲基吡啶-4-氨基甲酸叔丁酯合成路线 （共 4 条）
反应条件
in tert-butyl alcohol T=20°C;
参考文献
INCYTE CORPORATION
Patent: WO2007/38215 A1, 2007 ;
Location in patent: Page/Page column 92 ;
WO 2007/038215 A1
反应条件
n-butyllithium 1.) THF, hexane, 0 deg C, 3 h, 2.) THF, hexane, 20 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Hands, David; Bishop, Brian; Cameron, Mark; Edwards, John S.; Cottrell, Ian F.; Wright, Stanley H. B.
Synthesis, 1996 , # 7 p. 877 - 882
反应条件
1: 1.) t-BuLi / 1.) THF, pentane, -40 deg C, 1 h, 2.) THF, pentane, 20 deg C, 1 h 2: 5.5 M HCl / 1 h / 45 - 50 °C View Scheme
参考文献
Hands, David; Bishop, Brian; Cameron, Mark; Edwards, John S.; Cottrell, Ian F.; Wright, Stanley H. B.
Synthesis, 1996 , # 7 p. 877 - 882
反应条件
1: 1.) t-BuLi / 1.) THF, pentane, -40 deg C, 1 h, 2.) THF, pentane, 20 deg C, 1 h
2: 5.5 M HCl / 1 h / 45 - 50 °C
View Scheme
参考文献
Hands, David; Bishop, Brian; Cameron, Mark; Edwards, John S.; Cottrell, Ian F.; Wright, Stanley H. B.
Synthesis, 1996 , # 7 p. 877 - 882
