反应条件
1: 1.) NaOH / 1.) DMPU, room temperature, 15 min, 2.) DMPU
2: 94 percent / NaH, DMPU / dimethylformamide / 2 h / 100 °C
3: 74 percent / aq. NaOH / methanol / Heating
4: 88 percent / tetrahydrofuran / 0.75 h / Ambient temperature
5: 1.) PPh3, Pd(OAc)2, aq. Na2CO3 / 1.) DME, room temperature, 1 h, 2.) DME, reflux
6: 99 percent / POCl3 / acetonitrile / 0.5 h / Heating
View Scheme
参考文献
Geen, Graham R.; Mann, Inderjit S.; Mullane, M. Valerie; McKillop, Alexander
Tetrahedron, 1998 , vol. 54, # 33 p. 9875 - 9894
