N-(三甲基硅基)-2-(三甲基硅氧基)-4-嘧啶胺合成路线 （共 18 条）
反应条件
in diphenylether; octane; n-heptane; toluene T=80 - 150°C; optical yield given as percent dediastereoselective reaction;
参考文献
Chang, Young-Kil; Lee, Jaeheon; Park, Gha-Seung; Lee, Moonsub; Park, Chul Hyun; Kim, Han Kyong; Lee, Gwansun; Lee, Bo-Young; Baek, Ju Yuel; Kim, Kwan Soo
Tetrahedron, 2010 , vol. 66, # 30 p. 5687 - 5691
反应条件
t-butyldimethylsiyl triflate; ammonia 1.) CH3CN, 25 deg C, 12 h, 2.) 25 deg C, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Jung, Michael E.; Castro, Claire; Gardiner, John M.
Tetrahedron Letters, 1991 , vol. 32, # 41 p. 5717 - 5720
反应条件
trimethylsilyl trifluoromethanesulfonate 1) 1,1,2-trichloroethane, r.t., 30 min, 2) 113 deg C, 18 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chou; Heath; Patterson; Poteet; Lakin; Hunt
Synthesis, 1992 , # 6 p. 565 - 570
反应条件
trimethylsilyl iodide in dichloromethane Vorbrueggen reaction;
参考文献
Goodyear, Michael D.; Hill, Malcolm L.; West, Jono P.; Whitehead, Andrew J.
Tetrahedron Letters, 2005 , vol. 46, # 49 p. 8535 - 8538
参考文献
Goodyear, Michael D.; Hill, Malcolm L.; West, Jono P.; Whitehead, Andrew J.
Tetrahedron Letters, 2005 , vol. 46, # 49 p. 8535 - 8538
反应条件
trimethylsilyl trifluoromethanesulfonate 1) 1,1,2-trichloroethane, r.t., 30 min, 2) 113 deg C, 18 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chou; Heath; Patterson; Poteet; Lakin; Hunt
Synthesis, 1992 , # 6 p. 565 - 570
反应条件
in toluene
1.) RT, overnight, 2.) 70 deg C, 3 h;
参考文献
Schroeder, Alan C.; Hughes, Robert G.; Bloch, Alexander
Journal of Medicinal Chemistry, 1981 , vol. 24, # 9 p. 1078 - 1083
反应条件
chloro-trimethyl-silane; potassium iodide in acetonitrile
16 h; Ambient temperature; Yield given;
参考文献
Ubasawa; Takashima; Sekiya
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 1 p. 142 - 143
