1: 93 percent / DBU / acetonitrile / 0.33 h / 40 - 45 °C 2: 1.) NaOH / 1.) DMPU, room temperature, 15 min, 2.) DMPU 3: 93 percent / NaH, DMPU / dimethylformamide / 2 h / 100 °C 4: 82 percent / aq. NaOH / methanol / Heating 5: 35 percent / PPh3, Pd(OAc)2, aq. Na2CO3 / 1,2-dimethoxy-ethane / Heating View Scheme