(S)-1-苯基-1,2,3,4-四氢-2-异喹啉甲酸乙酯合成路线 (共 22 条)
反应条件
sodium ethanolate in water; N,N-dimethyl-formamide; toluene T=20°C; 8 h; Heating; Product distribution / selectivity;
参考文献
Astellas Pharma Inc.
Patent: EP1714965 A1, 2006 ;
Location in patent: Page/Page column 9; 10 ;
反应条件
potassium 2-methyl-2-butoxide in toluene T=90°C; 3 h; Product distribution / selectivity;
参考文献
WO2008/77357 A2, ;
Page/Page column 6-7 ;