4-羧基苯硼酸频那醇酯合成路线

F. HOFFMANN-LA ROCHE AG; HERMANN, Johannes Cornelius; LUCAS, Matthew C.; LUK, Kin-Chun Thomas; PADILLA, Fernando; WANNER, Jutta; XIE, Wenwei; ZHANG, Xiaohu
Patent: WO2012/163724 A1, 2012 ;
Location in patent: Page/Page column 71 ;

765-30-0环丙胺+

180516-87-44-羧基苯硼酸频那醇酯

827614-68-6N-(环丙基)-4-(4,4,5,5-四甲基-1,3,2-恶硼-2基)苯甲酰胺

参考文献

US2012/59162 A1, ;

Page/Page column 52-53 ;

18282-59-23,4-二氯溴苯+

180516-87-44-羧基苯硼酸频那醇酯

7111-64-04-(3,4-二氯苯基)苯甲酸

参考文献

Hajduk, Philip J.; Dinges, Juergen; Miknis, Gregory F.; Merlock, Megan; Middleton, Tim; Kempf, Dale J.; Egan, David A.; Walter, Karl A.; Robins, Terry S.; Shuker, Suzy B.; Holzman, Thomas F.; Fesik, Stephen W.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 20 p. 3144 - 3150

106-41-24-溴苯酚+

180516-87-44-羧基苯硼酸频那醇酯

58574-03-14'-羟基联苯-4-羧酸

参考文献

Hajduk, Philip J.; Dinges, Juergen; Miknis, Gregory F.; Merlock, Megan; Middleton, Tim; Kempf, Dale J.; Egan, David A.; Walter, Karl A.; Robins, Terry S.; Shuker, Suzy B.; Holzman, Thomas F.; Fesik, Stephen W.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 20 p. 3144 - 3150