T=740°C; P=3 - 3.5 Torr; Product distributionMechanism;

<b>Multi-step reaction with 4 steps<br /> </b>1: 92 percent / NaOAc / 3 h / Heating<br />2: 98 percent / H₂SO₄ / 4 h / Heating<br />3: 1.) tert-BuLi, tetramethylethylenediamine / 1.) Et₂O, hexane, -78 deg C, 45 min, 2.) 0 deg C, 14 h<br />4: 75 percent / NaOAc / methanol / 12 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 95 percent / Et₃N, DMAP / CH₂Cl₂ / 2.5 h<br />2: 92 percent / NaOAc / 3 h / Heating<br />3: 98 percent / H₂SO₄ / 4 h / Heating<br />4: 1.) tert-BuLi, tetramethylethylenediamine / 1.) Et₂O, hexane, -78 deg C, 45 min, 2.) 0 deg C, 14 h<br />5: 75 percent / NaOAc / methanol / 12 h / Ambient temperature<br /> <br /> &nbsp;