1: rac-2-methylpiperazine With [2,2']bipyridinyl; nickel diacetate; sodium hydride; 1,1-dimethylpropan-1-ol in tetrahydrofuran T=65°C; 2 h; 2: 4-methyl-chlorobenzene With styrene in tetrahydrofuran T=65°C; 10 h;

bis (triortho-tolylphosphine)palladium(II) chloride; sodium t-butanolate in toluene T=100°C; 3 h;