3-(羟基甲基)-5-硝基苯酚合成路线 （共 5 条）
反应条件
sodium tetrahydroborate; iodine in tetrahydrofuran T=20°C; 6 h;
参考文献
Hartung, Ingo V.; Rude, Mathew A.; Schnarr, Nathan A.; Hunziker, Daniel; Khosla, Chaitan
Journal of the American Chemical Society, 2005 , vol. 127, # 32 p. 11202 - 11203
反应条件
1: 86 percent / hexamethylphosphoric acid triamide / 20 h / 85 °C 2: 95 percent / AcOH; HBr / 20 h / Heating 3: 79 percent / NaBH4; I2 / tetrahydrofuran / 6 h / 20 °C View Scheme
参考文献
Hartung, Ingo V.; Rude, Mathew A.; Schnarr, Nathan A.; Hunziker, Daniel; Khosla, Chaitan
Journal of the American Chemical Society, 2005 , vol. 127, # 32 p. 11202 - 11203
反应条件
1: 95 percent / AcOH; HBr / 20 h / Heating 2: 79 percent / NaBH4; I2 / tetrahydrofuran / 6 h / 20 °C View Scheme
参考文献
Hartung, Ingo V.; Rude, Mathew A.; Schnarr, Nathan A.; Hunziker, Daniel; Khosla, Chaitan
Journal of the American Chemical Society, 2005 , vol. 127, # 32 p. 11202 - 11203
反应条件
manganese(IV) oxide in dichloromethane; acetone T=20°C; 24 h;
参考文献
Hartung, Ingo V.; Rude, Mathew A.; Schnarr, Nathan A.; Hunziker, Daniel; Khosla, Chaitan
Journal of the American Chemical Society, 2005 , vol. 127, # 32 p. 11202 - 11203
反应条件
1: 89 percent / potassium carbonate / acetone / 15 h / Heating
2: 99 percent / pyridinium chlorochromate / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Peng, Weimin; Blagg, Brian S. J.
Organic Letters, 2006 , vol. 8, # 5 p. 975 - 978
