1.1: water; sodium carbonate; methanol / 2 h / 25 - 30 °C 2.1: hydrogen; methanesulfonic acid / 5 palladium on charcoal / acetone / 20 °C / 2585.81 Torr 2.2: 0.5 h / 25 - 30 °C View Scheme

1: sodium hydrogencarbonate / methanol; water / 40 - 50 °C 2: methanesulfonic acid; 5 palladium on charcoal; hydrogen / water; acetone / 25 - 30 °C View Scheme

1.1: potassium carbonate; methanol / 25 - 35 °C 1.2: 25 - 30 °C 2.1: hydrogen / 5 Pd(II)/C(eggshell) / water; acetone / 25 - 35 °C / Inert atmosphere 3.1: sodium hydroxide / ethyl acetate; water / 0.33 h / 25 - 30 °C / pH 7 - 10 3.2: 10.5 h / 20 - 25 °C View Scheme

water; potassium carbonate in methanol T=20 - 40°C; Product distribution / selectivity;

methanol; sodium hydroxide T=60 - 65°C;