2-乙酰基-3,5-双(苄氧基)苯酚合成路线 （共 35 条）
反应条件
potassium carbonate in acetone Heating;
参考文献
Dewick, Paul M.
Synthetic Communications, 1981 , vol. 11, # 10 p. 853 - 858
反应条件
1: 82 percent / K2CO3 / dimethylformamide / 96 h / 70 °C 2: 74 percent / KOH; pyridine / bis-(2-hydroxy-ethyl) ether / 4 h / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 31 p. 7257 - 7265
反应条件
1: 82 percent / K2CO3 / dimethylformamide / 96 h / 70 °C 2: 74 percent / KOH; pyridine / bis-(2-hydroxy-ethyl) ether / 4 h / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 31 p. 7257 - 7265
反应条件
1: sodium hydride; water / N,N-dimethyl-formamide; mineral oil / 17 h / 0 - 20 °C 2: dichloromethane / 1.5 h / 0 °C 3: titanium tetrachloride / dichloromethane / 1.5 h / -5 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 69, p. 823 - 832
反应条件
1: dichloromethane / 1.5 h / 0 °C 2: titanium tetrachloride / dichloromethane / 1.5 h / -5 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 69, p. 823 - 832
反应条件
1: pyridine / 4 h / 120 °C / |Reflux 2: sodium hydride; water / N,N-dimethyl-formamide; mineral oil / 17 h / 0 - 20 °C 3: dichloromethane / 1.5 h / 0 °C 4: titanium tetrachloride / dichloromethane / 1.5 h / -5 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 69, p. 823 - 832
反应条件
1: 72 percent / pyridine / 20 °C 2: 61 percent / tert-butylimino-tri(pyrrolidino)phosphorane / dioxane / 24 h / 100 °C View Scheme
参考文献
Caldwell, Stuart T.; Petersson, Hanna M.; Farrugia, Louis J.; Mullen, William; Crozier, Alan; Hartley, Richard C.
Tetrahedron, 2006 , vol. 62, # 31 p. 7257 - 7265
反应条件
1: aq. KOH / ethanol 2: 1.3 g / H2 / 10percent Pd-C / ethyl acetate / Ambient temperature; atmospheric pressure View Scheme
参考文献
Jain, A. C.; Paliwal, Poonam
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 416 - 418
反应条件
triethylammonium formate; palladium on activated charcoal 2 h; Ambient temperature;
参考文献
Krishnamurty, H. G.; Ghosh, Sanjukta; Sathyanarayana, S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 1253 - 1254
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20 °C 2: iodine / dimethyl sulfoxide / 110 °C 3: 3,3-dimethyldioxirane / dichloromethane; acetone / 0 °C 4: acetic acid / water / 110 °C 5: potassium carbonate / N,N-dimethyl-formamide / 5 h / 20 °C 6: methanol; sodium methylate / 5 h / 20 °C 7: hydrogen; palladium(II) oxide hydrate / tetrahydrofuran; methanol / 6 h / 20 °C View Scheme
参考文献
Yamasaki, Kazuaki; Hishiki, Ryogo; Kato, Eisuke; Kawabata, Jun
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 1 p. 17 - 21
