2-乙酰基-3,5-双(苄氧基)苯酚合成路线 （共 35 条）
反应条件
aqueous KOH in tetrahydrofuran; ethanol
参考文献
Dynapol
Patent: US4267165 A1, 1981 ;
Title/Abstract Full Text Show Details
Dynapol
Patent: US4290957 A1, 1981 ;
反应条件
1: 96 percent / BF3*Et2O; 4 Angstroem molecular sieves / CH2Cl2 / -78 - 20 °C 2: 84 percent / dioxane; aq. NaOH / 24 h / 20 °C 3: 84 percent / I2 / dimethylsulfoxide / 0.5 h / Heating 4: 100 percent / H2 / Pd-C / ethanol; ethyl acetate / 20 °C View Scheme
参考文献
Kumazawa; Kimura; Matsuba; Sato; Onodera
Carbohydrate Research, 2001 , vol. 334, # 3 p. 183 - 193
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20 °C 2: iodine / dimethyl sulfoxide / 110 °C View Scheme
参考文献
Yamasaki, Kazuaki; Hishiki, Ryogo; Kato, Eisuke; Kawabata, Jun
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 1 p. 17 - 21
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20 °C 2: iodine / dimethyl sulfoxide / 110 °C 3: 3,3-dimethyldioxirane / dichloromethane; acetone / 0 °C 4: hydrogen; palladium(II) oxide hydrate / tetrahydrofuran; methanol / 3 h / 20 °C View Scheme
参考文献
Yamasaki, Kazuaki; Hishiki, Ryogo; Kato, Eisuke; Kawabata, Jun
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 1 p. 17 - 21
反应条件
1: 68 percent / piperidine / ethanol / 6 h / Heating 2: sodium acetate; 3: 79 percent / 1) thallium (III)nitrate trihydrate; 2) 10percent hydrochloric acid; / methanol / 1) 32-35 deg C; 8 h; 2) reflux; 3 h; 4: 97 percent / hydrogenolyse / 10percent Pd-C / methanol View Scheme
参考文献
Tsukayma, Masao; Fujimoto, Kunihiro; Horie, Tokunaru; Masumura, Mitsuo; Nakayama, Mitsuru
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, p. 136 - 141
反应条件
1: 91 percent 2: 89 percent / H2 / 10percent Pd/C View Scheme
参考文献
Tsukayama, Masao; Kawamura, Yasuhiko; Tamaki, Hiroto; Kubo, Tomoya; Horie, Tokunaru
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 3 p. 826 - 832
反应条件
1: 95 percent / H2 / Pd/C / methanol; ethyl acetate / 20 °C 2: 96 percent / I2; periodic acid / ethanol; H2O / 0.03 h / 45 °C / microwave irradiation View Scheme
参考文献
Hossain, Mohammad M.; Kawamura, Yasuhiko; Yamashita, Kazuyo; Tsukayama, Masao
Tetrahedron, 2006 , vol. 62, # 36 p. 8625 - 8635
参考文献
Caldwell, Stuart T.; Petersson, Hanna M.; Farrugia, Louis J.; Mullen, William; Crozier, Alan; Hartley, Richard C.
Tetrahedron, 2006 , vol. 62, # 31 p. 7257 - 7265
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20 °C 2: iodine / dimethyl sulfoxide / 110 °C 3: 3,3-dimethyldioxirane / dichloromethane; acetone / 0 °C View Scheme
参考文献
Yamasaki, Kazuaki; Hishiki, Ryogo; Kato, Eisuke; Kawabata, Jun
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 1 p. 17 - 21
反应条件
1: aq. KOH / ethanol
2: 1.3 g / H2 / 10percent Pd-C / ethyl acetate / Ambient temperature; atmospheric pressure
3: 295 mg / BF3*Et2O, DMF / 1.5 h / Heating
View Scheme
参考文献
Jain, A. C.; Paliwal, Poonam
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 416 - 418
