2-重氮基-5,5-二甲基-1,3-环己二酮合成路线 （共 26 条）
反应条件
1: silver tetrafluoroborate / toluene / 24 h / 20 °C / Inert atmosphere; Ionic liquid
2: toluene-4-sulfonic acid / toluene / 2 h / Inert atmosphere; Reflux
View Scheme
参考文献
Xia, Likai; Lee, Yong Rok; Kim, Sung Hong; Lyoo, Won Seok
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 5 p. 1554 - 1558
反应条件
rhodium (II) acetate; toluene-4-sulfonic acid
1.) fluorobenzene, 10 h; 2.) benzene, reflux, 1 h; Yield given. Multistep reaction;
参考文献
Pirrung, Michael C.; Lee, Yong Rok
Tetrahedron Letters, 1994 , vol. 35, # 34 p. 6231 - 6234
反应条件
1: 83 percent / methanol / Irradiation
2: 1.) NaBH4, 2.) thionyl chloride / 1.) methanol, 0 deg C, 0.5 h, 2a.) from 0 deg C to 20 deg C, 3 h, 2b.) 65 deg C, 1 h
3: 1,8-diazabicyclo<5.4.0>undec-7-ene / CH2Cl2 / 3 h / 0 - 20 °C
4: 96 percent / base / H2O
5: 68 percent / oxalyl chloride / benzene / 1.) 0 deg C, 0.5 h, 2.) 70 deg C, 1 h
View Scheme
参考文献
Magnus, Philip; Quagliato, Dominick
Journal of Organic Chemistry, 1985 , vol. 50, # 10 p. 1621 - 1626
反应条件
benzophenone in ethyl acetate-n-hexane; m-xylene
参考文献
Union Carbide Corporation
Patent: US4175135 A1, 1979 ;
反应条件
benzophenone in ethyl acetate-n-hexane; m-xylene
参考文献
Union Carbide Corporation
Patent: US4209532 A1, 1980 ;
反应条件
Rh2(Piv)4
T=20°C; 3 h;
参考文献
Lee, Yong Rok; Hwang, Jae Cheol
European Journal of Organic Chemistry, 2005 , # 8 p. 1568 - 1577
反应条件
silver tetrafluoroborate in toluene
T=70°C; 5 h; Inert atmosphereIonic liquid;
参考文献
Xia, Likai; Lee, Yong Rok; Kim, Sung Hong; Lyoo, Won Seok
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 5 p. 1554 - 1558
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in toluene
T=70°C; 10 h; Inert atmosphere;
参考文献
Xia, Likai; Lee, Yong Rok
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 11-12 p. 2361 - 2374
反应条件
in toluene
T=80 - 120°C; 0.316667 h; Inert atmosphereMicrowave irradiation;
参考文献
Presset, Marc; Coquerel, Yoann; Rodriguez, Jean
Organic Letters, 2009 , vol. 11, # 24 p. 5706 - 5709
反应条件
1: xylene / 1.25 h / Heating
2: TsOH / benzene / 2 h / Heating
View Scheme
参考文献
Capuano,L. et al.
Chemische Berichte, 1976 , vol. 109, p. 2456 - 2461
