1: With di-isopropyl azodicarboxylate; diphenyl phosphoryl azide; triphenylphosphine in tetrahydrofuran T=0 - 55°C; Inert atmosphereSchlenk technique; 2: With water T=55°C; 1 h;

1: With trifluoroacetic acid; zinc T=0 - 30°C; 1 h; 2: With sodium hydroxide in dichloromethane; water T=0 - 20°C; 1 h;

ammonia in water

1.1: hydroxylamine hydrochloride; sodium hydrogencarbonate / methanol / 24 h / 20 °C 2.1: zinc; trifluoroacetic acid / 1 h / 0 - 30 °C 2.2: 1 h / 0 - 20 °C View Scheme