2,6-二甲基-3-羟甲基吡啶合成路线 （共 7 条）
反应条件
(NH4)2S2O8 1 h; Heating;
参考文献
Amrollahi Biyouki, Mohammad A.; Smith, Robin A. J.; Bedford, Jennifer J.; Leader, John P.
Synthetic Communications, 1998 , vol. 28, # 20 p. 3817 - 3825
反应条件
1: 85 percent / CH2Cl2 / 1.5 h 2: 41 percent / aq. ammonium persulfate / 1 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 28, # 20 p. 3817 - 3825
反应条件
1: 78 percent / 1) m-CPBA, 2) HCl gas / acetone 2: 85 percent / CH2Cl2 / 1.5 h 3: 41 percent / aq. ammonium persulfate / 1 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 28, # 20 p. 3817 - 3825
反应条件
manganese(IV) oxide in ethanol 17 h; Reflux; Reagent/catalyst;
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281399 A1, 2013 ;
Location in patent: Paragraph 0732; .0735; 0740; 0760; 0770; 0752 ;
反应条件
1: With thionyl chloride in dichloromethane T=20°C; 21 h; 2: With water; sodium hydrogencarbonate
参考文献
ASKA Pharmaceutical Co., Ltd.
Patent: EP2036905 A1, 2009 ;
Location in patent: Page/Page column 50 ;
反应条件
triethylamine in dichloromethane T=20°C; 1 h;
参考文献
BIOVITRUM AB (publ)
Patent: WO2009/147211 A1, 2009 ;
Location in patent: Page/Page column 27 ;
WO 2009/147211 A1
反应条件
hydrogen bromide
4 h; Heating;
参考文献
Mobinikhaledi; Foroughifar
Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 2 p. 405 - 412
