1-{2-[4-(2-溴-6-甲氧基-3,4-二氢-1-萘基)苯氧基]乙基}吡咯烷合成路线 （共 5 条）
反应条件
pyridinium hydrobromide perbromide in tetrahydrofuran; dichloromethane
参考文献
Pfizer Products Inc.
Patent: EP1004306 A2, 2000 ;
EP 1004306 A2
反应条件
pyridinium bromide perbromide in tetrahydrofuran 60 h;
参考文献
Pfizer Inc
Patent: US2005/70512 A1, 2005 ;
Location in patent: Page/Page column 22-23 ;
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; water 18 h; Reflux;
参考文献
GLENMARK GENERICS LIMITED; KHAN, Mubeen Ahmed; TRIVEDI, Nikhil Rasiklal; KANDASAMY, Nagan Nirmalan; PATIL, Dayaghan Gangadhar; PANDEY, Vipin Kumar; SINHA, Sukumar
Patent: WO2010/125578 A2, 2010 ;
Location in patent: Page/Page column 20; 21 ;
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; water 18 h; Heating / reflux;
参考文献
Pfizer Inc
Patent: US2005/70512 A1, 2005 ;
Location in patent: Page/Page column 23 ;
反应条件
hydrogenchloride in tetrahydrofuran; diethyl ether; dichloromethane; water; ethyl acetate
参考文献
Pfizer, Inc.
Patent: US6153622 A1, 2000 ;
