(3S,4E)-3-羟基-7-[(三苯基甲基)硫基]-4-庚烯酸合成路线 （共 7 条）
反应条件
lithium hydroxide in methanol; water
参考文献
Li, Khan W.; Wu, Jerry; Xing, Wenning; Simon, Julian A.
Journal of the American Chemical Society, 1996 , vol. 118, # 30 p. 7237 - 7238
反应条件
1.1: BuLi / tetrahydrofuran / -78 °C 1.2: Cp2ZrCl2 / tetrahydrofuran / -78 - 20 °C 2.1: 76 percent / NaOH View Scheme
参考文献
Li, Khan W.; Wu, Jerry; Xing, Wenning; Simon, Julian A.
Journal of the American Chemical Society, 1996 , vol. 118, # 30 p. 7237 - 7238
反应条件
1: 78 percent / Cs2CO3 2: 91 percent / DIBAL 3: 74 percent / (COCl)2, DMSO, Et3N 4: 99 percent / Ti(IV) complex with (S)-(-)-binaphthyl amino alcohol 5: 100 percent / LiOH / methanol; H2O View Scheme
参考文献
Fuse, Shinichiro; Okada, Kumiko; Iijima, Yusuke; Munakata, Asami; MacHida, Kazuhiro; Takahashi, Takashi; Takagi, Motoki; Shin-Ya, Kazuo; Doi, Takayuki
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 10 p. 3825 - 3833
反应条件
1: 74 percent / (COCl)2, DMSO, Et3N 2: 99 percent / Ti(IV) complex with (S)-(-)-binaphthyl amino alcohol 3: 100 percent / LiOH / methanol; H2O View Scheme
参考文献
Li, Khan W.; Wu, Jerry; Xing, Wenning; Simon, Julian A.
Journal of the American Chemical Society, 1996 , vol. 118, # 30 p. 7237 - 7238
反应条件
1: 91 percent / DIBAL 2: 74 percent / (COCl)2, DMSO, Et3N 3: 99 percent / Ti(IV) complex with (S)-(-)-binaphthyl amino alcohol 4: 100 percent / LiOH / methanol; H2O View Scheme
参考文献
Li, Khan W.; Wu, Jerry; Xing, Wenning; Simon, Julian A.
Journal of the American Chemical Society, 1996 , vol. 118, # 30 p. 7237 - 7238
反应条件
1: 78 percent / Cs2CO3 2: 91 percent / DIBAL 3: 74 percent / (COCl)2, DMSO, Et3N 4: 99 percent / Ti(IV) complex with (S)-(-)-binaphthyl amino alcohol 5: 100 percent / LiOH / methanol; H2O View Scheme
参考文献
Li, Khan W.; Wu, Jerry; Xing, Wenning; Simon, Julian A.
Journal of the American Chemical Society, 1996 , vol. 118, # 30 p. 7237 - 7238
反应条件
1: 95 percent / (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate, DIEA 2: 98 percent / LiOH 3: EDCl, DMAP, TsOH 4: 84 percent / I2 / methanol; H2O View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 30 p. 7237 - 7238
