1: 91 percent / DIBAL 2: 74 percent / (COCl)2, DMSO, Et3N 3: 99 percent / Ti(IV) complex with (S)-(-)-binaphthyl amino alcohol 4: 100 percent / LiOH / methanol; H2O View Scheme

1: 91 percent / DIBAL 2: 74 percent / (COCl)2, DMSO, Et3N 3: 95 percent / Ti(IV) complex with (R)-(-)-binaphthyl amino alcohol 4: 100 percent / LiOH / methanol; H2O 5: 98 percent / (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate, DIEA 6: 93 percent / LiOH 7: 62 percent / DIAD, PPh3, TsOH*H2O / tetrahydrofuran / 2 h / 0 °C 8: 84 percent / I2 / methanol; H2O View Scheme