2-氨基-1,3-苯并噻唑-6-磺酰胺合成路线 （共 13 条）
反应条件
isopentyl nitrite in 1,4-dioxane 2 h; Heating;
参考文献
Nagarajan, Srinivasan R.; De Crescenzo, Gary A.; Getman, Daniel P.; Lu, Hwang-Fun; Sikorski, James A.; Walker, Jeffrey L.; McDonald, Joseph J.; Houseman, Kathryn A.; Kocan, Geralyn P.; Kishore, Nandini; Mehta, Pramod P.; Funkes-Shippy, Christie L.; Blystone, Lisa
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 22 p. 4769 - 4777
反应条件
1: 85 percent / isoamylnitrite / dioxane / 2 h / Heating 2: thionyl chloride / 1,2-dichloro-ethane; dimethylformamide / 1.5 h / Heating View Scheme
参考文献
Nagarajan, Srinivasan R.; De Crescenzo, Gary A.; Getman, Daniel P.; Lu, Hwang-Fun; Sikorski, James A.; Walker, Jeffrey L.; McDonald, Joseph J.; Houseman, Kathryn A.; Kocan, Geralyn P.; Kishore, Nandini; Mehta, Pramod P.; Funkes-Shippy, Christie L.; Blystone, Lisa
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 22 p. 4769 - 4777
反应条件
1: potassium hydroxide / tetrahydrofuran / 1 h / 60 °C
2: hydrazine hydrate / tetrahydrofuran / 1 h / 60 °C
View Scheme
参考文献
Sethi, Kalyan K.; Verma, Saurabh M.; Prasanthi, Naru; Annapurna, Mathrusri M.
Letters in Drug Design and Discovery, 2011 , vol. 8, # 9 p. 774 - 777
