1-(氯甲基)-2,5-二甲基-3-硝基苯合成路线 （共 6 条）
反应条件
chlorosulfonic acid; sodium chloride
参考文献
Winchester; Popp
Journal of Heterocyclic Chemistry, 1975 , vol. 12, # 3 p. 547 - 549
反应条件
hydrogenchloride; acetic acid in water
参考文献
Agence Nationale de Val orisation de la Recherche (ANVAR)
Patent: US4266060 A1, 1981 ;
反应条件
hydrogenchloride; 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; acetic acid in water
2.5 h; Heating;
参考文献
Rivalle, Christian; Ducrocq, Claire; Lhoste, Jean-Marc; Bisagni, Emile
Journal of Organic Chemistry, 1980 , vol. 45, p. 2176 - 2180
反应条件
1: 53 percent / CH3COOH, hexamethylenetetramine, HCl / H2O / 2.5 h / Heating
2: 72 percent / piperidine / pyridine / 24 h / Heating
View Scheme
参考文献
Rivalle, Christian; Ducrocq, Claire; Lhoste, Jean-Marc; Bisagni, Emile
Journal of Organic Chemistry, 1980 , vol. 45, p. 2176 - 2180
参考文献
Winchester; Popp
Journal of Heterocyclic Chemistry, 1975 , vol. 12, # 3 p. 547 - 549
反应条件
(i) aq. EtOH, (ii) H2, PtO2, MeOH; Multistep reaction;
参考文献
Winchester; Popp
Journal of Heterocyclic Chemistry, 1975 , vol. 12, # 3 p. 547 - 549
