2-联苯-(4-甲氧基)羧酸合成路线 （共 21 条）
反应条件
1: H2SO4 / methanol / 4 h / Heating 2: 4.5 N HCl / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 25 p. 3985 - 3992
反应条件
1: 1.) H2 / 1.) PtO2 2: sodium hydride / methanol View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 842 - 848
反应条件
1: 1.) n-BuLi, 2.) ZnCl2, 3.) MeMgBr, Ni(PPh3)2Cl2 2: 29 percent / 1 N NaOH / ethanol / 18 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 45, # 11 p. 1870 - 1874
反应条件
1: 1.) n-BuLi, 2.) ZnCl2, 3.) MeMgBr, Ni(PPh3)2Cl2 2: 29 percent / 1 N NaOH / ethanol / 18 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 45, # 11 p. 1870 - 1874
反应条件
hydrogenchloride Heating; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 25 p. 3985 - 3992
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / tetrahydrofuran; water / 20 - 80 °C / |Schlenk technique; |Inert atmosphere 2: sodium hydroxide; water / tetrahydrofuran / 80 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 47 p. 15836 - 15840
反应条件
sodium hydride in methanol
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 842 - 848
反应条件
2,2'-azo-bisisobutyronitrile; diphenyl diselenide; tri-n-butyl-tin hydride 1 h; Heating;
参考文献
Tetrahedron, , vol. 62, # 33 p. 7824 - 7837
参考文献
Sci. Rep. Tohoku Univ., Ser. 1: Phys., Chem., Astron., , vol. # 38, p. 101,141,142
反应条件
hydrazine in ethanol T=60°C; 4 h;
参考文献
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1719756 A1, 2006 ;
Location in patent: Page/Page column 49 ;
EP 1719756 A1
