2-(3-溴-4-甲氧基苯基)乙醇合成路线 （共 7 条）
反应条件
dimethylsulfide borane complex in tetrahydrofuran T=0°C; 3 h;
参考文献
MERCK SHARP andamp;; DOHME CORP.; PASTERNAK, Alexander; SHAHRIPOUR, Aurash; TANG, Haifeng; TEUMELSAN, Nardos, H.; YANG, Lihu; ZHU, Yuping; WALSH, Shawn, P.
Patent: WO2010/129379 A1, 2010 ;
Location in patent: Page/Page column 76 ;
WO 2010/129379 A1
反应条件
trifluoroacetic acid; sodium t-butanolate; Pd(dba)2 in tetrahydrofuran; methanol; dichloromethane; toluene
参考文献
Symyx Technologies
Patent: US2002/72632 A1, 2002 ;
反应条件
potassium carbonate in acetone T=40°C; 5 h;
参考文献
Sviridov, Sergey I.; Vasil'ev, Andrei A.; Sergovskaya, Natalia L.; Chirskaya, Marina V.; Shorshnev, Sergey V.
Tetrahedron, 2006 , vol. 62, # 11 p. 2639 - 2647
反应条件
hydrogenchloride; sodium borohydride; Calcium chloride in tetrahydrofuran; water
参考文献
Schering Aktiengesellschaft
Patent: US6200970 B1, 2001 ;
US 6200970 B1
反应条件
1: 44 percent / Br2; NaHCO3 / methanol; CH2Cl2 / 0 - 5 °C 2: 93 percent / K2CO3 / acetone / 5 h / 40 °C View Scheme
参考文献
Sviridov, Sergey I.; Vasil'ev, Andrei A.; Sergovskaya, Natalia L.; Chirskaya, Marina V.; Shorshnev, Sergey V.
Tetrahedron, 2006 , vol. 62, # 11 p. 2639 - 2647
反应条件
1: Br2 / acetic acid / 40 - 45 °C 2: LiAlH4 View Scheme
参考文献
Fujio, Mizue; Funatsu, Kimito; Goto, Mutsuo; Seki, Yoji; Mishima, Masaaki; Tsuno, Yuho
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 3 p. 1091 - 1096
反应条件
lithium aluminium tetrahydride Title compound not separated from byproducts;
参考文献
Fujio, Mizue; Funatsu, Kimito; Goto, Mutsuo; Seki, Yoji; Mishima, Masaaki; Tsuno, Yuho
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 3 p. 1091 - 1096
