4-(1,1-二甲基乙基)苯丙醛合成路线 （共 17 条）
反应条件
[RhCl(η2:η2-cycloocta-1,5-diene)]2; 1,3-bis-(diphenylphosphino)propane; hydrogen in water; toluene T=120°C; P=7500.75 Torr; 20 h; Overall yield = 78 percentChromat.; regioselective reaction;
参考文献
Tetrahedron Letters, , vol. 54, # 18 p. 2209 - 2211
反应条件
1: 4-tert-butyl-toluene With anhydrous iron chloride in toluene T=20°C; 0.5 h; 2: acetaldehyde With zinc oxide T=130 - 180°C; 1.5 h; Autoclave; 3: With hydrogen; palladium-on-charcoal in ethanol T=50°C; P=15001.5 Torr; Autoclave; Product distribution / selectivity;
参考文献
US2010/256421 A1, ;
Page/Page column 3 ;
反应条件
[rhodium(I)(carbonyl)2(acetylacetonate)]; 1,3-bis[(diphenylphosphino)oxy]-1,3-diphenylpropane; hydrogen in toluene T=60°C; P=18751.9 Torr; 4 h; Schlenk techniqueHigh pressure; Catalytic behavior; regioselective reaction;
参考文献
Applied Organometallic Chemistry, , vol. 27, # 5 p. 313 - 317
反应条件
(R)-2,2'-dihydroxy-1,1'-binaphthyl; [Rh(1,5-cyclooctadienyl)(μ-OCH3)]2 in toluene T=40°C; P=11251.1 Torr; 115 h; Title compound not separated from byproducts.;
参考文献
Journal of the Chemical Society, Dalton Transactions, , # 14 p. 2067 - 2068
反应条件
1: 59 percent / nickel(II) bromide trihydrate; stainless steel (Fe/Ni/Cr, 72/18/10); nickel / 1,2-dibromoethane; tetrabutylammonium bromide / dimethylformamide; pyridine / 5.5 h / 70 °C / Electrolysis 2: aqueous HCl / dimethylformamide; pyridine / 0.5 h / 20 °C View Scheme
参考文献
Organic Letters, , vol. 5, # 24 p. 4701 - 4703
反应条件
1: (i) , (ii) (catalytic hydrogenation) 2: Zn, aq. AcOH / Cob(I)alamin / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 61, # 7 p. 2560 - 2578
反应条件
acetic acid; zinc; cob(I)alamin Ambient temperature;
参考文献
Helvetica Chimica Acta, , vol. 61, # 7 p. 2560 - 2578
反应条件
boron trifluoride diethyl etherate; titanium tetrachloride T=-30°C;
参考文献
Bulletin de la Societe Chimique de France, , p. 1194 - 1198
反应条件
dimethylsulfide; oxygen; 2-methylpropane-2-thiol 1) benzene, irradiation, 2 h, 2) MeOH, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 33, # 1 p. 83 - 84
反应条件
acridine acid; dimethylsulfide multistep reaction; other carboxylic acids; other solvents, also with phenanthridine; Product distributionMechanism;
参考文献
Tetrahedron Letters, , vol. 33, # 1 p. 83 - 84
