1-苄基-1H-吡咯-2-羧酸合成路线 (共 4 条)
反应条件
dimethylaluminum chloride in hexane; toluene T=20°C; Friedel-Crafts reaction; P=22502.3 Torr; 3 h; regioselective reaction;
参考文献
Nemoto, Koji; Onozawa, Satoru; Egusa, Naoki; Morohashi, Naoya; Hattori, Tetsutaro
Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4512 - 4514
反应条件
water; potassium hydroxide in methanol Reflux;
参考文献
Mochona, Bereket; Le, Laine; Gangapuram, Madhavi; Mateeva, Nelly; Ardley, Tiffany; Redda, Kinfe K.
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 6 p. 1367 - 1371
反应条件
potassium hydroxide in dimethyl sulfoxide
参考文献
Mai; Artico, Marino; Esposito; Ragno; Sbardella; Massa
Farmaco, 2003 , vol. 58, # 3 p. 231 - 241
反应条件
1: in diethyl ether 24 h; Inert atmosphere; 2: With water; sodium hydroxide in ethanol 5 h; Reflux;
参考文献
Kerr, Daniel J.; White, Jonathan M.; Flynn, Bernard L.
Journal of Organic Chemistry, 2010 , vol. 75, # 21 p. 7073 - 7084