1: propionic acid methyl ester With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: tert-butyldimethylsilyl chloride With N,N,N',N',N'',N''-hexamethylphosphoric triamide in tetrahydrofuran; hexane
T=-78 - 20°C; Title compound not separated from byproducts;
参考文献
Denmark, Scott E.; Wynn, Thomas; Beutner, Gregory L.
Journal of the American Chemical Society, 2002 , vol. 124, # 45 p. 13405 - 13407