2,3-二氢-3-羟基-2-苯基-1H-异吲哚-1-酮合成路线 （共 13 条）
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol T=0 - 5°C; 2 h;
参考文献
Ishihara; Kiyota; Goto
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 11 p. 3024 - 3030
反应条件
1: benzoylaminobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78 - 0°C; 0.6 h; Inert atmosphere; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere;
参考文献
Jozwiak; Ciechanska
Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 2 p. 357 - 362
反应条件
1: isopropyl alcohol / |Heating 2: |Reflux 3: hydrogenchloride / water / |Heating View Scheme
参考文献
Jha, Amitabh; Chou, Ting-Yi; ALJaroudi, Zainab; Ellis, Bobby D.; Cameron, T. Stanley
Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 848 - 857
反应条件
1: acetic anhydride; sodium acetate / 90 °C 2: sodium tetrahydroborate / methanol / 1 h / |Cooling with ice View Scheme
参考文献
Jha, Amitabh; Chou, Ting-Yi; ALJaroudi, Zainab; Ellis, Bobby D.; Cameron, T. Stanley
Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 848 - 857
反应条件
1: dichloromethane / 0.5 h / 20 °C 2: acetic anhydride; sodium acetate / 90 °C 3: sodium tetrahydroborate / methanol / 1 h / |Cooling with ice View Scheme
参考文献
Jha, Amitabh; Chou, Ting-Yi; ALJaroudi, Zainab; Ellis, Bobby D.; Cameron, T. Stanley
Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 848 - 857
反应条件
1: |Reflux 2: hydrogenchloride / water / |Heating View Scheme
参考文献
Ukhin; Suponitsky; Belousova; Orlova
Russian Chemical Bulletin, 2009 , vol. 58, # 12 p. 2478 - 2487
Izv. Akad. Nauk, Ser. Khim., 2009 , # 12 p. 2399 - 2407,9
反应条件
1: isopropyl alcohol / |Heating 2: |Reflux 3: hydrogenchloride / water / |Heating View Scheme
参考文献
Ukhin; Suponitsky; Belousova; Orlova
Russian Chemical Bulletin, 2009 , vol. 58, # 12 p. 2478 - 2487
Izv. Akad. Nauk, Ser. Khim., 2009 , # 12 p. 2399 - 2407,9
反应条件
1: 67 percent / potassium borohydride / methanol / Ambient temperature 2: 61 percent / 15 percent hydrochloric acid / 1.) room temperature, 3 d, 2.) reflux, 2 min View Scheme
参考文献
Epsztajn, Jan; Jozwiak, Andrzej; Szczesniak, Aleksandra K.
Tetrahedron, 1993 , vol. 49, # 4 p. 929 - 938
反应条件
potassium borohydride in methanol Ambient temperature;
参考文献
Epsztajn, Jan; Jozwiak, Andrzej; Szczesniak, Aleksandra K.
Tetrahedron, 1993 , vol. 49, # 4 p. 929 - 938
参考文献
Mali, R. S.; Yeola, Suresh N.
Synthesis, 1986 , # 9 p. 755 - 757
