1: With n-butyllithium in tetrahydrofuran T=-78 - -5°C; 1 h; Cooling with acetone-dry ice; 2: With oxygen in tetrahydrofuran T=-71°C; 0.666667 h; Cooling with acetone-dry ice; 3: With phosphorous acid trimethyl ester in tetrahydrofuran T=-71°C; 0.25 h; Cooling with acetone-dry ice;
参考文献
G.D. Searle and Co.
Patent: EP1223167 A2, 2002 ;
Location in patent: Page 33-34 ;
