4-苯基-3-丁炔-2-酮合成路线 （共 131 条）
反应条件
1: 4-phenyl-3-butyn-2-one With boron trifluoride diethyl etherate in diethyl ether
T=0°C; 0.05 h; Inert atmosphere;
2: 4-ethylidene-2,2,6,6-tetramethyl-3,5-dioxa-2,6-disilaheptane in diethyl ether
T=0 - 20°C; 4 h; Inert atmosphere; Overall yield = 94 percent;
参考文献
Lopez-Reyes, Morelia E.; Lopez-Cortes, Jose G.; Ortega-Alfaro, M. Carmen; Toscano, R. Alfredo; Alvarez-Toledano, Cecilio
Tetrahedron, 2013 , vol. 69, # 35 p. 7365 - 7372
反应条件
1: hydroxylamine-O-sulphonic acid / H2O / 0.58 h / 0 °C
2: H3C-COONa, K2Te / 4 h / Ambient temperature
View Scheme
参考文献
Lucchesini, Francesco; Bertini, Vincenzo
Synthesis, 1983 , # 10 p. 824 - 827
反应条件
hydrogen; Lindlar's catalyst in pentane
P=760 Torr; Ambient temperature;
参考文献
Boldrini, Gian Paolo; Bortolotti, Michele; Mancini, Fabrizio; Tagliavini, Emilio; Trombini, Claudio; Umani-Ronchi, Achille
Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5820 - 5826
反应条件
quinoline; ammonium hypophosphorous acid; palladium on activated charcoal in water; benzene
3 h;
参考文献
Khai, Bui The; Arcelli, Antionio
Chemische Berichte, 1993 , vol. 126, # 10 p. 2265 - 2268
反应条件
hydrogen; ethylenediamine; Pd on pumice in tetrahydrofuran
1.66667 h;
参考文献
Gruttadauria, Michelangelo; Liotta, Leonarda F.; Noto, Renato; Deganello, Giulio
Tetrahedron Letters, 2001 , vol. 42, # 10 p. 2015 - 2017
反应条件
triethylamine in benzene
T=20°C;
参考文献
Bianchi, Giorgio; Gandolfi, Remo; Micheli, Carlo De
Journal of Chemical Research, Miniprint, 1981 , # 1 p. 135 - 158
反应条件
ammonium acetate; acetic acid in toluene
Bohlmann-Rahtz reaction; 20 h; Heating;
参考文献
Bagley, Mark C.; Dale, James W.; Bower, Justin
Chemical Communications, 2002 , # 16 p. 1682 - 1683
反应条件
Amberlyst 15 in toluene
T=50°C; Bohlmann-Rahtz pyridine synthesis;
参考文献
Bagley, Mark C.; Brace, Christian; Dale, James W.; Ohnesorge, Maren; Phillips, Nathan G.; Xiong, Xin; Bower, Justin
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 14 p. 1663 - 1671
参考文献
Weygand
Chemische Berichte, 1925 , vol. 58, p. 1478
反应条件
sodium carbonate in acetonitrile
T=120°C; 0.666667 h; microwave irradiation;
参考文献
Bagley, Mark C.; Hughes, David D.; Taylor, Paul H.
Synlett, 2003 , # 2 p. 259 - 261
