4-甲氧基-1,3-苯并二氧戊环合成路线 （共 26 条）
反应条件
hydrogenchloride; aluminium trichloride; benzene
anschliessend Hydrolyse;
参考文献
Campbell et al.
Journal of Organic Chemistry, 1951 , vol. 16, p. 1736,1740
反应条件
Behandeln des Reaktionsgemisches mit Wasser;
参考文献
Wagner et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 4983,4986
Full Text Show Details
Brownell; Weston
Journal of the American Chemical Society, 1951 , vol. 73, p. 4971
反应条件
Behandeln des Reaktionsgemisches mit Wasser;
参考文献
Wagner et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 4983,4986
Full Text Show Details
Brownell; Weston
Journal of the American Chemical Society, 1951 , vol. 73, p. 4971
反应条件
acetic anhydride
T=0 - 20°C;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/46120 A2, 2004 ;
Location in patent: Page 171 ;
WO 2004/046120 A2
参考文献
Daukshas, V. K.; Udrenaite, E. B.; Gineitite, V. L.; Rukshenas, A. Yu.; Komovnikova, G. G.; Barauskaite, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , p. 993 - 996
Khimiya Geterotsiklicheskikh Soedinenii, 1980 , vol. 16, # 10 p. 1315 - 1319
反应条件
bromine; iron in tetrachloromethane
T=20°C;
参考文献
Daukshas, V. K.; Udrenaite, E. B.; Gineitite, V. L.; Rukshenas, A. Yu.; Komovnikova, G. G.; Barauskaite, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , p. 993 - 996
Khimiya Geterotsiklicheskikh Soedinenii, 1980 , vol. 16, # 10 p. 1315 - 1319
