1: With potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide T=110°C; Heck reaction; 20 h; 2: With sodium hydroxide; water in N,N-dimethyl-formamide T=50 - 80°C;

palladium 10 on activated carbon; hydrogen in tetrahydrofuran T=20°C;