2,2,2-三氟-1-呋喃-2-乙酮合成路线 （共 7 条）
反应条件
water; Dess-Martin periodane in dichloromethane T=20°C; 3 h;
参考文献
Schering Corporation
Patent: US2004/106794 A1, 2004 ;
Location in patent: Page 92 ;
US 20040106794 A1
反应条件
1: (trifluoromethyl)-trimethylsilane With silver monofluoride T=20°C; 2 h; 2: furan-2-carbonyl chloride With 4-(N,N-dimethlyamino)pyridine in dichloromethane T=20°C; 48 h; Further stages.;
参考文献
Kremlev, Mikhail M.; Mushta, Aleksej I.; Tyrra, Wieland; Naumann, Dieter; Fischer, Hendrik T.M.; Yagupolskii, Yurii L.
Journal of Fluorine Chemistry, 2007 , vol. 128, # 11 p. 1385 - 1389
反应条件
bis(trifluoromethyl)cadmium*glyme in pyridine T=0°C; 8 h;
参考文献
Journal of Fluorine Chemistry, , vol. 56, # 2 p. 215 - 237
参考文献
Glukhovtsev, V. G.; Il'in, Yu. V.; Ignatenko, A. V.; Brezhnev, L. Yu.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1987 , vol. 36, # 12 p. 2631 - 2633
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1987 , # 12 p. 2834 - 2837
反应条件
in pyridine T=0°C; 6 h;
参考文献
Journal of Fluorine Chemistry, , vol. 56, # 2 p. 215 - 237
参考文献
Journal of Fluorine Chemistry, , vol. 56, # 2 p. 215 - 237
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-phenyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 2: 2,2,2-trifluoro-1-(furan-2-yl)ethanone in tetrahydrofuran; diethyl ether T=20°C; 1 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
