4-硝基[1,1-联苯]-2-羧酸合成路线 (共 13 条)
反应条件
potassium carbonate; 2-dicyclohexylphosphino-1,1'-biphenyl; palladium diacetate in acetonitrile T=90°C; Suzuki coupling reaction; 20 h;
参考文献
Synthesis, , # 8 p. 1043 - 1046
反应条件
1: 76 percent / aq. NaOH; KMnO4 / 3 h / 50 °C 2: 74 percent / aq. K2CO3; Cy2P(bi-Ph) / Pd(OAc)2 / acetonitrile / 20 h / 90 °C View Scheme
参考文献
Synthesis, , # 8 p. 1043 - 1046
反应条件
potassium permanganate
参考文献
Journal of the Chemical Society, , p. 554 - 562
反应条件
nitric acid; acetic acid
参考文献
Journal of the American Chemical Society, , vol. 76, p. 4543,4544
反应条件
1: aq. K2CO3, Pd(OAc)2 / acetone / Heating 2: KMnO4 / pyridine; H2O / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 1 p. 217 - 223
反应条件
aminosulfonic acid; nitric acid T=50 - 60°C; 1 h;
参考文献
Australian Journal of Chemistry, , vol. 43, # 1 p. 203 - 207
参考文献
Journal of the Chemical Society, , p. 2213,2216
反应条件
nitric acid 70 deg C, 2 h; Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 842 - 848
反应条件
hydrogen; platinum(IV) oxide in ethyl acetate
参考文献
Neustadt, Bernard R.; Smith, Elizabeth M.; Lindo, Neil; Nechuta, Terry; Bronnenkant, Alan; Wu, Arthur; Armstrong, Lydia; Kumar, Chandra
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 17 p. 2395 - 2398
反应条件
1: 1.) H2 / 1.) PtO2 2: sodium hydride / methanol View Scheme
参考文献
Glover, Stephen A.; Golding, Stephen L.; Goosen, Andre; McCleland, Cedric W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 842 - 848