4-甲基-1,2,3-噻重氮-5-羧酸乙酯合成路线 （共 11 条）
反应条件
thionyl chloride in dichloromethane T=10 - 20°C; 23 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 21 p. 5821 - 5824
反应条件
thionyl chloride in dichloromethane T=0 - 20°C;
参考文献
Arkivoc, , vol. 2010, # 2 p. 330 - 339
反应条件
1: AcOH / methanol 2: SOCl2 View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 46, p. 1057 - 1063
反应条件
1: 2: With thionyl chloride in dichloromethane Hurd-Mori reaction;
参考文献
Asian Journal of Chemistry, , vol. 23, # 9 p. 4064 - 4066
参考文献
Journal of Heterocyclic Chemistry, , vol. 13, p. 301 - 304
Journal of Heterocyclic Chemistry, , vol. 14, p. 567 - 571
反应条件
in gaseous matrix T=409.9°C; further temperature: 643 K; MechanismProduct distribution;
参考文献
Torres, M.; Clement, A.; Strausz, O. P.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1983 , vol. 38, # 10 p. 1208 - 1212
反应条件
hydrazine hydrate in ethanol T=50°C; 2 h;
参考文献
Archiv der Pharmazie, , vol. 333, # 10 p. 347 - 354
反应条件
sodium hydroxide in methanol T=20°C; 16 h;
参考文献
Fan, Zhijin; Shi, Zugui; Zhang, Haike; Liu, Xiufeng; Bao, Lili; Ma, Lin; Zuo, Xiang; Zheng, Qinxiang; Mi, Na
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 10 p. 4279 - 4286
反应条件
sodium tetrahydroborate in ethanol T=20°C; 2 h; Inert atmosphere;
参考文献
Porcal, Williams; Hernandez, Paola; Gonzalez, Mercedes; Ferreira, Ana; Olea-Azar, Claudio; Cerecetto, Hugo; Castro, Ana
Journal of Medicinal Chemistry, 2008 , vol. 51, # 19 p. 6150 - 6159
反应条件
in ethanol; cyclohexane
参考文献
Schering Aktiengesellschaft
Patent: US4177054 A1, 1979 ;
