3,4,5-三甲氧基苯硼酸合成路线 （共 30 条）
反应条件
1: With n-butyllithium in tetrahydrofuran T=-78°C; Inert atmosphere; 2: With boric acid trimethyl ester in tetrahydrofuran T=-78 - 20°C; Inert atmosphere;
参考文献
Rosen, Brad M.; Wilson, Daniela A.; Wilson, Christopher J.; Peterca, Mihai; Won, Betty C.; Huang, Chenghong; Lipski, Linda R.; Zeng, Xiangbing; Ungar, Goran; Heiney, Paul A.; Percec, Virgil
Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17500 - 17521
反应条件
Mg in tetrahydrofuran Mg (reflux), THF, B(OCH)3, bromobenzene-compound (-10°C) or n-butyllithium, B(OCH3)3, -78°C, THF;
参考文献
Rosen, Brad M.; Wilson, Daniela A.; Wilson, Christopher J.; Peterca, Mihai; Won, Betty C.; Huang, Chenghong; Lipski, Linda R.; Zeng, Xiangbing; Ungar, Goran; Heiney, Paul A.; Percec, Virgil
Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17500 - 17521
反应条件
1: With boric acid trimethyl ester in tetrahydrofuran T=-78 - 20°C; 2: With hydrogenchloride in water
参考文献
Gerbino, Dario C.; Mandolesi, Sandra D.; Schmalz, Hans-Guenther; Podesta, Julio C.
European Journal of Organic Chemistry, 2009 , # 23 p. 3964 - 3972
反应条件
1: With tert.-butyl lithium in tetrahydrofuran T=-78°C; 2: With boric acid trimethyl ester in tetrahydrofuran T=-78 - 20°C; Further stages.;
参考文献
Fukuda, Tsutomu; Sudo, Ei-ichi; Shimokawa, Kozue; Iwao, Masatomo
Tetrahedron, 2008 , vol. 64, # 2 p. 328 - 338
反应条件
1: 5-iodo-1,2,3-trimethoxybenzene With tert.-butyl lithium in tetrahydrofuran T=-78°C; 1 h; 2: boric acid trimethyl ester in tetrahydrofuran T=-78°C; 1 h;
参考文献
Tetrahedron Letters, , vol. 44, # 24 p. 4443 - 4446
反应条件
1.1: NaNO2; concd. H2SO4 / H2O / 5 - 10 °C 1.2: 70 percent / aq. CuBr / 0.5 h / Heating 2.1: nBuLi / tetrahydrofuran; hexane / 1 h / -85 °C 2.2: 64 percent / trimethylborate / tetrahydrofuran / 18 h / 20 °C View Scheme
参考文献
European Journal of Organic Chemistry, , # 15 p. 2829 - 2839
反应条件
water T=25°C; Equilibrium constant;
参考文献
Heterocycles, , vol. 74, # C p. 219 - 223
反应条件
water T=25°C; Equilibrium constant;
参考文献
Heterocycles, , vol. 74, # C p. 219 - 223
反应条件
water T=25°C; Equilibrium constant;
参考文献
Heterocycles, , vol. 74, # C p. 219 - 223
反应条件
water T=25°C; Equilibrium constant;
参考文献
Heterocycles, , vol. 74, # C p. 219 - 223
