1: With n-butyllithium in tetrahydrofuran; hexane T=-65°C; 0.166667 h; 2: With tri-isopropoxy-borane in tetrahydrofuran T=-65°C; 0.166667 h; 3: With hydrogenchloride in water

1.1: 75 percent / hydrochloric acid / acetonitrile / 24 h / 20 °C 2.1: n-buthyllithium / hexane; tetrahydrofuran / 0.17 h / -65 °C 2.2: triisopropyl borate / tetrahydrofuran / 0.17 h / -65 °C 2.3: hydrochloric acid / H2O View Scheme

dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; potassium fluoride; palladium diacetate in tetrahydrofuran; water T=20°C; Suzuki-Miyaura coupling; 2 h;