4-氟-N-(3-(1-甲基哌啶-4-基)-1H-吲哚-5-基)苯甲酰胺盐酸盐合成路线 （共 5 条）
反应条件
sulfuric acid; hydrogen; Rh(acac)2(CO)2 T=100°C; P=45003.6 Torr; 72 h;
参考文献
Schmidt, Axel M.; Eilbracht, Peter
Journal of Organic Chemistry, 2005 , vol. 70, # 14 p. 5528 - 5535
反应条件
1: 84 percent / NaH / dimethylsulfoxide / 0.5 h / 20 °C 2: 95 percent / TPPPS; H2; aq.H2SO4 / Rh(acac)2(CO)2 / 72 h / 100 °C / 45003.6 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 14 p. 5528 - 5535
反应条件
1: 78 percent / CuI; 1,10-phenanthroline; Cs2CO3 / dimethylformamide / 68 h / 80 °C 2: 95 percent / TPPPS; H2; aq.H2SO4 / Rh(acac)2(CO)2 / 72 h / 100 °C / 45003.6 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 14 p. 5528 - 5535
反应条件
1: 99 percent / DMAP; NEt3 / tetrahydrofuran / 1 h / 20 °C 2: 78 percent / CuI; 1,10-phenanthroline; Cs2CO3 / dimethylformamide / 68 h / 80 °C 3: 95 percent / TPPPS; H2; aq.H2SO4 / Rh(acac)2(CO)2 / 72 h / 100 °C / 45003.6 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 14 p. 5528 - 5535
反应条件
1: 99 percent / DMAP; NEt3 / tetrahydrofuran / 1 h / 20 °C 2: 78 percent / CuI; 1,10-phenanthroline; Cs2CO3 / dimethylformamide / 68 h / 80 °C 3: 95 percent / TPPPS; H2; aq.H2SO4 / Rh(acac)2(CO)2 / 72 h / 100 °C / 45003.6 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 14 p. 5528 - 5535
