4-[乙酰基(甲基)氨基]-4-苯基哌啶-1-氨基甲酸叔丁酯合成路线 （共 6 条）
反应条件
potassium hydroxide; tetrabutylammomium bromide in tetrahydrofuran
T=40°C; 24 h;
参考文献
Giardina; Grugni, Mario; Rigolio, Roberto; Vassallo, Marco; Erhard, Karl; Farina, Carlo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2307 - 2310
反应条件
1: 80 percent / tetrahydrofuran
2: 80 percent / H2SO4 / acetonitrile
3: H2 / Pd/C / ethanol
4: TEA / dimethylformamide
5: 70 percent / KOH, TBAB / tetrahydrofuran / 24 h / 40 °C
View Scheme
参考文献
Giardina; Grugni, Mario; Rigolio, Roberto; Vassallo, Marco; Erhard, Karl; Farina, Carlo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2307 - 2310
反应条件
1: 80 percent / H2SO4 / acetonitrile
2: H2 / Pd/C / ethanol
3: TEA / dimethylformamide
4: 70 percent / KOH, TBAB / tetrahydrofuran / 24 h / 40 °C
View Scheme
参考文献
Giardina; Grugni, Mario; Rigolio, Roberto; Vassallo, Marco; Erhard, Karl; Farina, Carlo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2307 - 2310
反应条件
1: 80 percent / tetrahydrofuran
2: 80 percent / H2SO4 / acetonitrile
3: H2 / Pd/C / ethanol
4: TEA / dimethylformamide
5: 70 percent / KOH, TBAB / tetrahydrofuran / 24 h / 40 °C
View Scheme
参考文献
Giardina; Grugni, Mario; Rigolio, Roberto; Vassallo, Marco; Erhard, Karl; Farina, Carlo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2307 - 2310
反应条件
1: H2 / Pd/C / ethanol
2: TEA / dimethylformamide
3: 70 percent / KOH, TBAB / tetrahydrofuran / 24 h / 40 °C
View Scheme
参考文献
Giardina; Grugni, Mario; Rigolio, Roberto; Vassallo, Marco; Erhard, Karl; Farina, Carlo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2307 - 2310
反应条件
1: TEA / dimethylformamide
2: 70 percent / KOH, TBAB / tetrahydrofuran / 24 h / 40 °C
View Scheme
参考文献
Giardina; Grugni, Mario; Rigolio, Roberto; Vassallo, Marco; Erhard, Karl; Farina, Carlo
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2307 - 2310
