4-羟基-2-甲氧基苯甲醛合成路线 （共 36 条）
反应条件
potassium hydroxide T=100°C; 0.25 h;
参考文献
Achenbach, Hans; Stoecker, Markus; Constenla, Manuel A.
Phytochemistry (Elsevier), 1988 , vol. 27, # 6 p. 1835 - 1842
反应条件
1: potassium carbonate / acetone / 3 h / Reflux 2: potassium hydroxide / methanol / 12 h / 20 °C 3: hydrogenchloride / ethanol; water / 1 h / 40 °C 4: ethanol; water / 24 h / 180 °C View Scheme
参考文献
Jeon, Jae-Ho; Kim, Mi Ran; Kwon, Eun Mi; Lee, Na Ri; Jun, Jong-Gab
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 3 p. 1059 - 1062
反应条件
potassium carbonate in acetone Heating;
参考文献
Vaccaro, Wayne D.; Sher, Rosy; Davis Jr., Harry R.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 9 p. 1429 - 1437
反应条件
1: KOH; methanol 2: KMnO4 View Scheme
参考文献
Tiemann; Parrisius
Chemische Berichte, 1880 , vol. 13, p. 2366
反应条件
hydrogen; palladium 10 on activated carbon in ethanol; acetic acid T=20°C; P=3102.97 Torr; 14 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/37763 A1, 2005 ;
Location in patent: Page/Page column 128 ;
WO 2005/037763 A1
反应条件
sodium hydroxide; dihydrogen peroxide
参考文献
Birch,A.J. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1975 , p. 2492 - 2501
反应条件
methanol; potassium hydroxide
参考文献
Tiemann; Parrisius
Chemische Berichte, 1880 , vol. 13, p. 2366
参考文献
Blanksma
Recueil des Travaux Chimiques des Pays-Bas, 1910 , vol. 29, p. 411
反应条件
5A molecular sieve; pyridinium p-toluenesulfonate in dichloromethane T=20°C;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2004/26823 A1, 2004 ;
Location in patent: Page 39 ;
WO 2004/026823 A1
反应条件
sodium tetrahydroborate in methanol; water Ambient temperature;
参考文献
Mergler, M.; Tanner, R.; Gosteli, J.; Grogg, P.
Tetrahedron Letters, 1988 , vol. 29, # 32 p. 4005 - 4008
