4-氨基-N-丁基-苯磺酰胺合成路线 （共 6 条）
反应条件
iron; ammonium chloride in methanol; water T=20 - 70°C; 2.5 h;
参考文献
Rennison, David; Conole, Daniel; Tingle, Malcolm D.; Yang, Junpeng; Eason, Charles T.; Brimble, Margaret A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 24 p. 6629 - 6635
反应条件
sodium carbonate in methanol; water
参考文献
Noro Nordisk A/S
Patent: US6503949 B1, 2003 ;
US 6503949 B1
参考文献
Proceedings of the Royal Society of London, Series B: Biological Sciences, , vol. 133, p. 20,30
反应条件
1: diethyl ether 2: aqueous hydrochloric acid View Scheme
参考文献
Proceedings of the Royal Society of London, Series B: Biological Sciences, , vol. 133, p. 20,30
反应条件
1.1: hydrogenchloride; sodium nitrite / water / 0.17 h / -5 °C 1.2: 1.75 h / -5 - 0 °C 2.1: tetrahydrofuran / 0.5 h / 20 °C / |Inert atmosphere 3.1: iron; ammonium chloride / water; methanol / 2.5 h / 20 - 70 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 24 p. 6629 - 6635
反应条件
1: tetrahydrofuran / 0.5 h / 20 °C / |Inert atmosphere 2: iron; ammonium chloride / water; methanol / 2.5 h / 20 - 70 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 24 p. 6629 - 6635
