1,3-丙酮二羧酸二甲酯合成路线 （共 133 条）
反应条件
potassium fluoride; acetic acid in 1,4-dioxane
Heating;
参考文献
Takeuchi, Naoki; Okada, Naomi; Tobinaga, Seisho
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4355 - 4359
反应条件
potassium hydroxide in methanol
Yield given;
参考文献
Sands, Richard D.
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3362 - 3363
反应条件
potassium fluoride; acetic acid in benzene
参考文献
Diemer, Vincent; Chaumeil, Helene; Defoin, Albert; Carre, Christiane
Tetrahedron, 2010 , vol. 66, # 4 p. 918 - 929
反应条件
potassium fluoride; acetic acid in benzene
12 h; Heating; Yield given;
参考文献
Takeuchi, Naoki; Goto, Kaori; Sasaki, Yuki; Fujita, Takashi; Okazaki, Kohsuke; et al.
Heterocycles, 1992 , vol. 33, # 1 p. 357 - 374
反应条件
potassium fluoride; water; Fe2(CO)9; acetic acid
1.) benzene, 45 deg C, 30 min, 2.) benzene, reflux, 12 h; Yield given. Multistep reaction;
参考文献
Takeuchi, Naoki; Okazaki, Kousuke; Ohki, Junji; Tobinaga, Seisho
Heterocycles, 1984 , vol. 21, # 2 p. 615
反应条件
sodium hydride
1) THF, room temperature, 2) THF, room temperature, 1.5 h; Yield given. Multistep reaction;
参考文献
Covarrubias-Zuniga, Adrian
Synthetic Communications, 1998 , vol. 28, # 9 p. 1525 - 1530
反应条件
1: 61 percent / Na2CO3 / H2O / 24 h / 0 °C
2: 90 percent / Ag2CO3 / CHCl3 / 8 h / 45 °C
View Scheme
参考文献
Feng, Song; He, Xuchang; Yu, Gengli; Xia, Yu; Bai, Donglu
Organic Preparations and Procedures International, 2004 , vol. 36, # 2 p. 129 - 133
反应条件
sodium hydroxide in methanol; water
24 h; Ambient temperature;
参考文献
Bertz, Steven H.
Synthesis, 1980 , # 9 p. 708 - 710
反应条件
potassium fluoride; acetic acid in 1,4-dioxane
Heating;
参考文献
Takeuchi, Naoki; Okada, Naomi; Tobinaga, Seisho
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4355 - 4359
反应条件
potassium fluoride; acetic acid in benzene
12 h; Heating; Yield given;
参考文献
Takeuchi, Naoki; Goto, Kaori; Sasaki, Yuki; Fujita, Takashi; Okazaki, Kohsuke; et al.
Heterocycles, 1992 , vol. 33, # 1 p. 357 - 374
