N-(叔丁氧羰基)对甲苯磺酰胺合成路线 （共 29 条）
反应条件
1: 100 percent / K2CO3 / acetonitrile / 1.5 h / Heating
2: 306.2 mg / TFA / CH2Cl2 / 40 h / 20 °C
3: 89 percent / K2CO3 / acetonitrile / 6 h / Heating
View Scheme
参考文献
Terada, Yukiyoshi; Arisawa, Mitsuhiro; Nishida, Atsushi
Angewandte Chemie - International Edition, 2004 , vol. 43, # 31 p. 4063 - 4067
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C
1.2: 2 h / 20 °C
1.3: 20 °C
2.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere
View Scheme
参考文献
Benedetti, Erica; Simonneau, Antoine; Hours, Alexandra; Amouri, Hani; Penoni, Andrea; Palmisano, Giovanni; Malacria, Max; Goddard, Jean-Philippe; Fensterbank, Louis
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1908 - 1912
反应条件
1: 100 percent / K2CO3 / acetonitrile / 1.5 h / Heating
2: 306.2 mg / TFA / CH2Cl2 / 40 h / 20 °C
View Scheme
参考文献
Zheng, Huaiji; Huo, Xing; Zhao, Changgui; Jing, Peng; Yang, Juan; Fang, Bowen; She, Xuegong
Organic Letters, 2011 , vol. 13, # 24 p. 6448 - 6451
反应条件
1: potassium carbonate / acetone / 4 h / |Reflux
2: hydrogenchloride / 1,4-dioxane; water / 2 h / 20 °C
View Scheme
参考文献
Munoz-Bascon, Juan; Hernandez-Cervantes, Carmen; Padial, Natalia M.; Alvarez-Corral, Miriam; Rosales, Antonio; Rodriguez-Garcia, Ignacio; Oltra, J. Enrique
Chemistry - A European Journal, 2014 , vol. 20, # 3 p. 801 - 810
反应条件
1: 88 percent / diisopropylazodicarboxylate; PPh3 / tetrahydrofuran / 0 - 20 °C
2: 96 percent / TFA / CH2Cl2 / 24 h / 20 °C
View Scheme
参考文献
Stara, Irena G.; Kollarovic, Adrian; Teply, Filip; Stary, Ivo; Saman, David; Fiedler, Pavel
Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 4 p. 577 - 609
反应条件
1: (tosyl)NH(tert-butoxycarbonyl) With potassium carbonate in N,N-dimethyl-formamide
T=20°C; 1 h;
2: propargyl bromide in N,N-dimethyl-formamide
T=20°C; 2 h;
3: With trifluoroacetic acid in dichloromethane
T=20°C;
参考文献
Benedetti, Erica; Simonneau, Antoine; Hours, Alexandra; Amouri, Hani; Penoni, Andrea; Palmisano, Giovanni; Malacria, Max; Goddard, Jean-Philippe; Fensterbank, Louis
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1908 - 1912
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
Mitsunobu Displacement; Inert atmosphere;
参考文献
Ghosh, Nayan; Nayak, Sanatan; Sahoo, Akhila K.
Chemistry - A European Journal, 2013 , vol. 19, # 29 p. 9428 - 9433
反应条件
n-butyllithium
1.) THF, hexane, -78 deg C, 20 min, 2.) -78 deg C, 10 min, then to -10 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Genet, Jean-Pierre; Hajicek, Josef; Bischoff, Laurent; Greck, Christine
Tetrahedron Letters, 1992 , vol. 33, # 19 p. 2677 - 2680
反应条件
1: 100 percent / K2CO3 / acetonitrile / 1.5 h / Heating
2: 306.2 mg / TFA / CH2Cl2 / 40 h / 20 °C
3: 89 percent / K2CO3 / acetonitrile / Heating
View Scheme
参考文献
Terada, Yukiyoshi; Arisawa, Mitsuhiro; Nishida, Atsushi
Angewandte Chemie - International Edition, 2004 , vol. 43, # 31 p. 4063 - 4067
