苄氧羰基-L-酪氨酸苄酯三氟甲烷磺酸酯合成路线 （共 11 条）
反应条件
in dichloromethane T=-40°C; 2 h;
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7529 - 7530
反应条件
triethylamine in dichloromethane
参考文献
Fretz, Heinz
Tetrahedron Letters, 1996 , vol. 37, # 47 p. 8475 - 8478
反应条件
1: 16.5 g / Et3N / methanol / 2 h / 0 °C 2: 83 percent / CH2Cl2 / 2 h / -40 °C View Scheme
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7529 - 7530
反应条件
1: TsOH*H2O / benzene / 2 h / Heating 2: 16.5 g / Et3N / methanol / 2 h / 0 °C 3: 83 percent / CH2Cl2 / 2 h / -40 °C View Scheme
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7529 - 7530
反应条件
1: TsOH*H2O / benzene / 2 h / Heating 2: 16.5 g / Et3N / methanol / 2 h / 0 °C 3: 83 percent / CH2Cl2 / 2 h / -40 °C View Scheme
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7529 - 7530
反应条件
1: 95 percent / Cs2CO3 / methanol; H2O; dimethylformamide 2: 75 percent / 2,6-lutidine / CH2Cl2 / -40 °C View Scheme
参考文献
Wang, Wei; Obeyesekere, Nihal U.; McMurray, John S.
Tetrahedron Letters, 1996 , vol. 37, # 37 p. 6661 - 6664
反应条件
1: 95 percent / Cs2CO3 / methanol; H2O; dimethylformamide 2: 75 percent / 2,6-lutidine / CH2Cl2 / -40 °C View Scheme
参考文献
Wang, Wei; Obeyesekere, Nihal U.; McMurray, John S.
Tetrahedron Letters, 1996 , vol. 37, # 37 p. 6661 - 6664
反应条件
1: 89 percent / AcOK, 1,1'-bis(diphenylphosphino)ferrocene / Pd(OAc)2 / dimethylformamide / 3 h / 60 °C 2: 80 percent / BF3*Et2O / CH2Cl2; cyclohexane / 3 h / Ambient temperature 3: H2 / Pd/C View Scheme
参考文献
Wang, Wei; Obeyesekere, Nihal U.; McMurray, John S.
Tetrahedron Letters, 1996 , vol. 37, # 37 p. 6661 - 6664
反应条件
1: 89 percent / AcOK, 1,1'-bis(diphenylphosphino)ferrocene / Pd(OAc)2 / dimethylformamide / 3 h / 60 °C 2: 80 percent / BF3*Et2O / CH2Cl2; cyclohexane / 3 h / Ambient temperature 3: H2 / Pd/C 4: Na2CO3 / H2O; acetone / 2 h / Ambient temperature View Scheme
参考文献
Wang, Wei; Obeyesekere, Nihal U.; McMurray, John S.
Tetrahedron Letters, 1996 , vol. 37, # 37 p. 6661 - 6664
反应条件
1: 5 percent / Et3N / [PdCl2(dppf)] / dioxane / 80 °C 2: NaIO4; NH4OAc / acetone; H2O / 48 h / 20 °C 3: 207 mg / aq. NaOH / 1 h 4: 63 percent / hydrogen; aq. HCl / Pd(OH)2/C / ethanol / 19 h / 20 °C View Scheme
参考文献
Nakamura, Hiroyuki; Fujiwara, Masaru; Yamamoto, Yoshinori
Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 1 p. 231 - 235
