7,13-二-O-(三乙基硅烷基)-10-去乙酰基浆果赤霉素III合成路线 （共 2 条）
反应条件
1: sodium hydride / tetrahydrofuran / -5 - 0 °C 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 5 °C / |Inert atmosphere 3: sodium hydride / tetrahydrofuran / -5 - 0 °C 4: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 5 °C / |Inert atmosphere View Scheme
参考文献
FRESENIUS KABI ONCOLOGY LIMITED; LAHIRI, Saswata; GUPTA, Nitin; AZIM, Abul; PANDA, Nilendu; MISHRA, Bhuwan Bhaskar; SANGHANI, Sunil
Patent: US2014/58119 A1, 2014 ;
反应条件
1: sodium hydride / tetrahydrofuran / -5 - 0 °C 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 5 °C / |Inert atmosphere 3: sodium hydride / tetrahydrofuran / -5 - 0 °C 4: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 5 °C / |Inert atmosphere 5: 4-(N,N-dimethlyamino)pyridine / tetrahydrofuran / 0.5 h / 20 - 30 °C 6: hydrogenchloride / ethyl acetate / 0 °C View Scheme
参考文献
FRESENIUS KABI ONCOLOGY LIMITED; LAHIRI, Saswata; GUPTA, Nitin; AZIM, Abul; PANDA, Nilendu; MISHRA, Bhuwan Bhaskar; SANGHANI, Sunil
Patent: US2014/58119 A1, 2014 ;
