1: hydrochloric salt of m-aminophenylacetylene With sec.-butyllithium in tetrahydrofuran; cyclohexane T=0°C; 0.5 h; Inert atmosphere; 2: 6,7-bis(2-methoxyethoxy)-4-methoxyquinazoline in tetrahydrofuran; cyclohexane T=20°C; 15 h; 3: With hydrogenchloride in tetrahydrofuran; cyclohexane; water T=20°C; 1 h; Product distribution / selectivity;
1: With acetic acid in isopropyl alcohol 4 h; Reflux; 2: With hydrogenchloride in isopropyl alcohol T=20°C; pH=3.0 - 4.0; Product distribution / selectivity;
