3,4-二(2-甲氧基乙氧基)苯甲酸乙酯合成路线 （共 10 条）
反应条件
potassium carbonate; potassium iodide in acetone T=60°C; 19 h; Inert atmosphere;
参考文献
Shih, Kae-Shyang; Hsieh, Yu-Jung; Liu, Ching-Wei
Patent: US2010/267949 A1, 2010 ;
Location in patent: Page/Page column 6 ;
反应条件
potassium carbonate in acetonitrile 6 h; Reflux;
参考文献
Shenzhen Salubris Pharmaceuticals Co., Ltd.; Shanghai Institute of Pharmaceutical Industry; LI, Jianqi; ZHANG, Zixue; XIE, Peng; ZHANG, Qingwei
Patent: EP2592083 A1, 2013 ;
Location in patent: Paragraph 0258 ;
反应条件
tetra-(n-butyl)ammonium iodide; potassium carbonate in acetone 120 h; Heating;
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
potassium tert-butylate; tetrabutylammomium bromide in N,N-dimethyl-formamide T=30 - 40°C; 10 h;
参考文献
Zhang, Gengzhen; Zha, Linlin
Research on Chemical Intermediates, 2013 , vol. 39, # 6 p. 2303 - 2309
反应条件
potassium carbonate in acetone
反应条件
sulfuric acid; nitric acid in acetic acid T=20 - 70°C; 2 h;
参考文献
Zhang, Gengzhen; Zha, Linlin
Research on Chemical Intermediates, 2013 , vol. 39, # 6 p. 2303 - 2309
反应条件
1: acetic acid; nitric acid / 24 h / 20 °C 2: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 3: 84 percent / 12 h / 165 - 170 °C 4: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: acetic acid; nitric acid / 24 h / 20 °C 2: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 3: 84 percent / 12 h / 165 - 170 °C View Scheme
参考文献
Li, Shilei; Wang, Xiao; He, Yong; Zhao, Mingxia; Chen, Yurong; Xu, Jingli; Feng, Man; Chang, Jin; Ning, Hongyu; Qi, Chuanmin
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 293 - 301
反应条件
1: acetic acid; nitric acid / 24 h / 20 °C 2: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 3: 84 percent / 12 h / 165 - 170 °C 4: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C 5: pyridine / propan-2-ol View Scheme
参考文献
Knesl, Petr; Roeseling, Dirk; Jordis, Ulrich
Molecules, 2006 , vol. 11, # 4 p. 286 - 297
反应条件
1: acetic acid; nitric acid / 24 h / 20 °C 2: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
