4-氯-6,7-二(2-甲氧基乙氧基)喹唑啉合成路线 （共 24 条）
反应条件
N-ethyl-N,N-diisopropylamine; trichlorophosphate in toluene Heating;
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2539 - 2542
反应条件
1: potassium carbonate; tetrabutylammonium iodide / acetone / 120 h / Heating 2: acetic acid; nitric acid / 24 h / 20 °C 3: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 4: 84 percent / 12 h / 165 - 170 °C 5: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: acetic acid; nitric acid / 24 h / 20 °C 2: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 3: 84 percent / 12 h / 165 - 170 °C 4: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 2: 84 percent / 12 h / 165 - 170 °C 3: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: 85 percent / HNO3; Ac2O / 20 °C 2: 100 percent / H2 / Pd/C / ethanol 3: 90 percent / 160 °C 4: 100 percent / POCl3; diisopropylethylamine / toluene / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2539 - 2542
反应条件
1: 100 percent / H2 / Pd/C / ethanol 2: 90 percent / 160 °C 3: 100 percent / POCl3; diisopropylethylamine / toluene / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2539 - 2542
反应条件
1: 84 percent / 12 h / 165 - 170 °C 2: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: 98 percent / H2SO4 / Heating 2: 99 percent / K2CO3; TBAI / acetone / Heating 3: 85 percent / HNO3; Ac2O / 20 °C 4: 100 percent / H2 / Pd/C / ethanol 5: 90 percent / 160 °C 6: 100 percent / POCl3; diisopropylethylamine / toluene / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2539 - 2542
反应条件
1: 99 percent / K2CO3; TBAI / acetone / Heating 2: 85 percent / HNO3; Ac2O / 20 °C 3: 100 percent / H2 / Pd/C / ethanol 4: 90 percent / 160 °C 5: 100 percent / POCl3; diisopropylethylamine / toluene / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2539 - 2542
反应条件
triphenylphosphine on polystyrene; di-tert-butylazodicarboxylate in dichloromethane T=0 - 20°C; Mitsunobu reaction;
参考文献
Tetrahedron Letters, , vol. 50, # 14 p. 1600 - 1602
