5-(4-氯苯基)-3H-呋喃-2-酮合成路线 (共 6 条)
反应条件
trifluoroacetic acid in dichloromethane T=-5°C; 0.75 h;
参考文献
Pearce
Synthetic Communications, 1992 , vol. 22, # 11 p. 1627 - 1643
反应条件
acetyl chloride 0.5 h; Heating;
参考文献
Tsolomitis, A.; Sandris, C.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1545 - 1548
反应条件
1: 94 percent / benzylchlorobis(triphenylphosphine)palladium(II) / dimethylformamide / 16 h / 70 °C 2: 46 percent / CF3COOH / CH2Cl2 / 0.75 h / -5 °C View Scheme
参考文献
Pearce
Synthetic Communications, 1992 , vol. 22, # 11 p. 1627 - 1643
参考文献
Allen; Normington; Wilson
Canadian Journal of Research, 1934 , vol. 11, p. 386
Chem. Zentralbl., 1935 , vol. 106, # I p. 893
反应条件
hydrazine hydrate in ethanol 2 h; Ambient temperatureor heating, 2h;
参考文献
Hashem, A. I.; Shaban, M. E.; El-Kafrawy, A. F.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, p. 763 - 764
反应条件
aluminium trichloride
2 h; Heating;
参考文献
Hashem, A. I.; Shaban, M. E.; El-Kafrawy, A. F.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, p. 763 - 764