(S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; bis(.eta.(2)-ethylene)(2,4,-pentanedionato)rhodium in 1,4-dioxane; water T=100°C; Addition; 3 h;

1: 92 percent / α-chymotrypsin, aq. KCl / 120 h / Ambient temperature; pH 7.8 2: LiBH4 / 1,2-dimethoxy-ethane; methanol / 1 h / Heating 3: p-toluenesulfonic acid / toluene / 3.5 h / Heating View Scheme

1: LiBH4 / 1,2-dimethoxy-ethane; methanol / 1 h / Heating 2: p-toluenesulfonic acid / toluene / 3.5 h / Heating View Scheme

potassium phosphate; tetrakis-(ethylene)-μ,μ'-dichlorodirhodium(I); C25H27NO3S in 1,4-dioxane; water T=60°C; 1 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;