2-乙酰氧基-4-碘-1-甲氧基-苯合成路线 （共 12 条）
反应条件
12-phosphotungstic acid; iodine; nitrogen(IV) oxide in chloroform T=60°C; 2 h;
参考文献
Noda, Yumiki; Kashima, Mikito
Tetrahedron Letters, 1997 , vol. 38, # 35 p. 6225 - 6228
反应条件
1: 99 percent / pyridine / CH2Cl2 / 24 h / 0 - 18 °C 2: 73 percent / silver trifluoroacetate; iodine / CHCl3 / 5 h / 0 - 18 °C View Scheme
参考文献
Lambert, Joshua D.; Rice, Joseph E.; Hong, Jungil; Hou, Zhe; Yang, Chung S.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 873 - 876
反应条件
1: chloromethyl poly(styrene-co-1 percent divinylbenzene) resin; 3-hydroxy-4-methyloxyphenyl iodide With potassium iodide in N,N-dimethyl-formamide T=50°C; 24 h; 2: acetyl-bromide With zinc dibromide in dichloromethane T=20°C;
参考文献
Cironi, Pablo; Cuevas, Carmen; Albericio, Fernando; Alvarez, Mercedes
Tetrahedron, 2004 , vol. 60, # 39 p. 8669 - 8675
反应条件
chloro{1-tert-butyl-3-[(p-tolylsulfinyl)methyl]imidazol-2-ylidene}palladium(II) in acetic anhydride; acetic acid T=95°C; 16 h; Sealed tube; Overall yield = 58percent; Overall yield = 34 mg;
参考文献
Tato, Francisco; Garcia-Dominguez, Andres; Cardenas, Diego J.
Organometallics, 2013 , vol. 32, # 24 p. 7487 - 7494
反应条件
tetrachloromethane; iodine; mercury(II) oxide
参考文献
Tassilly; Leroide
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1907 , vol. 144, p. 758
Bulletin de la Societe Chimique de France, 1907 , vol. <4> 1, p. 932
Chem. Zentralbl., 1907 , vol. 78, # II p. 976
反应条件
1.1: Pd(OAc)2; PPh3; Ag2CO3 / acetonitrile / Heating 1.2: mCPBA; aq. NaHCO3 / CH2Cl2 1.3: H2 / Pd/C 2.1: 98 percent / KOH / methanol 3.1: 100 percent / CuSO4 / benzene / Heating 4.1: 34 percent / BBr3 / CH2Cl2 / -78 - 0 °C View Scheme
参考文献
Lambert, Joshua D.; Rice, Joseph E.; Hong, Jungil; Hou, Zhe; Yang, Chung S.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 873 - 876
反应条件
1: KOH-solution 2: sodium; alcohol / 90 °C View Scheme
参考文献
Tassilly; Leroide
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1907 , vol. 144, p. 758
Bulletin de la Societe Chimique de France, 1907 , vol. <4> 1, p. 932
Chem. Zentralbl., 1907 , vol. 78, # II p. 976
反应条件
1: aq. K2CO3 / methanol 2: 99 percent / K2CO3 / ethanol / Heating View Scheme
参考文献
Bushby; Lu
Synthesis, 2001 , # 5 p. 763 - 767
反应条件
1.1: NaOH; H2O / Heating 2.1: 63 percent / piperidine / CuI; (PPh3)4Pd / 1 h / 20 °C 3.1: borane*THF; cyclohexene / tetrahydrofuran / 1 h / 0 °C 3.2: 82 percent / HOAc / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Lawrence, Nicholas J.; Ghani, Fazni Abdul; Hepworth, Lucy A.; Hadfield, John A.; McGown, Alan T.; Pritchard, Robin G.
Synthesis, 1999 , # 9 p. 1656 - 1660
反应条件
potassium carbonate in methanol T=18°C; 16 h;
参考文献
Hanessian, Stephen; Guesne, Sebastien; Chenard, Etienne
Organic Letters, 2010 , vol. 12, # 8 p. 1816 - 1819
